姓名:朱彤
职称:见习副教授
办公地址:北京化工大学东校区综合楼B502 | ![]() |
教育背景:
2014.09–2018.06 南京大学,生物科学,学士
2018.09–2023.06 中国科学院微生物研究所,生物化学与分子生物学,博士工作经历:
2023.07–2026.01 中国科学院微生物研究所,博士后
2026.02–至今 北京化工大学生命科学与技术学院,见习副教授
主要研究领域:
蛋白质/多肽修饰酶的设计与应用
学术成绩:
主持国家自然科学基金青年科学基金项目(C类)1项,承担国家重点研发计划子课题1项。以第一作者(含共同一作)身份在Nat. Commun.、Natl. Sci. Rev.、ACS Catal.等国际学术期刊发表论文10余篇,获国家发明专利授权1项。
代表性著作:
Zhu T, Zhang X, Zhang H, Sun J, Cui Y, Wu B*. A single computationally redesigned enzyme enables traceless protein C-terminal functionalization. ACS Catalysis 2025, 15, 20909–20914.
Zhang H#, Zhu T#, Zhai Q, Chen Q, Zhang X, Chen Y, He W, Li J, Fan J, Tao J, Hu X, Qi L, Wang C, Liao K, Chen Y, Cui Y, Chen S*, Wu B*. Two-step computational redesign of Bacillus subtilis cellulase and β-glucanase for enhanced thermostability and activity. International Journal of Biological Macromolecules 2025, 285, 138274.
Zhu T, Wu B*. Repurposing amide bond-forming enzymes for non-native protein modification. ACS Catalysis 2024, 14, 15811–15826.
Zhu T, Sun J, Pang H, Wu B*. Computational enzyme redesign enhances tolerance to denaturants for peptide C-terminal amidation. JACS Au 2024, 4, 788–797.
Zhu T, Zhang X, Li R, Wu B*. Efficient production of peptidylglycine α-hydroxylating monooxygenase in yeast for protein C-terminal functionalization. International Journal of Biological Macromolecules 2024, 263, 130443.
Cui Y#, Chen Y#, Sun J#, Zhu T#, Pang H, Li C, Geng W, Wu B*. Computational redesign of a hydrolase for nearly complete PET depolymerization at industrially relevant high-solids loading. Nature Communications 2024, 15, 1417.
Zhu T#, Cui Y#, Geng W, Liu G, Jiang H, Li R, Wu B*. Creating an unusual glycine-rich motif in a peptide amidase leads to versatile protein C-terminal traceless functionalization. ACS Catalysis 2022, 12, 8019−8026.
Li R#, Schmidt M#, Zhu T#, Yang X, Feng J, Tian Y, Cui Y, Nuijens T*, Wu B*. Traceless enzymatic protein synthesis without ligation sites constraint. National Science Review 2022, 9, nwab158.
Zhu T#, Li R#, Sun J, Cui Y, Wu B*. Characterization and efficient production of a thermostable and organic solvent-stable cellulase from an oil reservoir. International Journal of Biological Macromolecules 2020, 159, 622–629.
Zhu T#, Song L#, Li R, Wu B*. Enzymatic clickable functionalization of peptides via computationally engineered peptide amidase. Chinese Chemical Letters 2018, 29, 1116–1118.
教师寄语:
珍视此刻,勇赴前程,笃志毅行,他日言胜。
招生要求:
敏锐、严谨、协作、坚韧

