朱彤

发布时间:2026-03-24

姓名:朱彤

 

职称:见习副教授

 

邮箱:2026500009@buct.edu.cn

 

办公地址:北京化工大学东校区综合楼B502


教育背景:

2014.092018.06   南京大学,生物科学,学士

2018.092023.06   中国科学院微生物研究所,生物化学与分子生物学,博士

工作经历:

2023.07–2026.01   中国科学院微生物研究所,博士后

2026.02–至今     北京化工大学生命科学与技术学院,见习副教授


主要研究领域:

蛋白质/多肽修饰酶的设计与应用


学术成绩:

主持国家自然科学基金青年科学基金项目(C类)1项,承担国家重点研发计划子课题1。以第一作者(含共同一作)身份在Nat. Commun.Natl. Sci. Rev.ACS Catal.等国际学术期刊发表论文10余篇,获国家发明专利授权1项。


代表性著作:

  1. Zhu T, Zhang X, Zhang H, Sun J, Cui Y, Wu B*. A single computationally redesigned enzyme enables traceless protein C-terminal functionalization. ACS Catalysis 2025, 15, 20909–20914.

  2. Zhang H#, Zhu T#, Zhai Q, Chen Q, Zhang X, Chen Y, He W, Li J, Fan J, Tao J, Hu X, Qi L, Wang C, Liao K, Chen Y, Cui Y, Chen S*, Wu B*. Two-step computational redesign of Bacillus subtilis cellulase and β-glucanase for enhanced thermostability and activity. International Journal of Biological Macromolecules 2025, 285, 138274.

  3. Zhu T, Wu B*. Repurposing amide bond-forming enzymes for non-native protein modification. ACS Catalysis 2024, 14, 15811–15826.

  4. Zhu T, Sun J, Pang H, Wu B*. Computational enzyme redesign enhances tolerance to denaturants for peptide C-terminal amidation. JACS Au 2024, 4, 788–797.

  5. Zhu T, Zhang X, Li R, Wu B*. Efficient production of peptidylglycine α-hydroxylating monooxygenase in yeast for protein C-terminal functionalization. International Journal of Biological Macromolecules 2024, 263, 130443.

  6. Cui Y#, Chen Y#, Sun J#, Zhu T#, Pang H, Li C, Geng W, Wu B*. Computational redesign of a hydrolase for nearly complete PET depolymerization at industrially relevant high-solids loading. Nature Communications 2024, 15, 1417.

  7. Zhu T#, Cui Y#, Geng W, Liu G, Jiang H, Li R, Wu B*. Creating an unusual glycine-rich motif in a peptide amidase leads to versatile protein C-terminal traceless functionalization. ACS Catalysis 2022, 12, 8019−8026.

  8. Li R#, Schmidt M#, Zhu T#, Yang X, Feng J, Tian Y, Cui Y, Nuijens T*, Wu B*. Traceless enzymatic protein synthesis without ligation sites constraint. National Science Review 2022, 9, nwab158.

  9. Zhu T#, Li R#, Sun J, Cui Y, Wu B*. Characterization and efficient production of a thermostable and organic solvent-stable cellulase from an oil reservoir. International Journal of Biological Macromolecules 2020, 159, 622–629.

  10. Zhu T#, Song L#, Li R, Wu B*. Enzymatic clickable functionalization of peptides via computationally engineered peptide amidase. Chinese Chemical Letters 2018, 29, 1116–1118. 



教师寄语:

珍视此刻,勇赴前程,笃志毅行,他日言胜。


招生要求:

敏锐、严谨、协作、坚韧