姓名：谢文升 职称：副教授 邮箱：xws@buct.edu.cn 办公地址：北京化工大学东校区科技大厦301室 |
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教育背景：
2020/09-2023/06，清华大学，化学系，博士，导师：危岩 （化学生物学）
2016/09-2018/06，清华大学，马克思主义学院，硕士，导师：朱安东 （政治经济学）
2015/09-2018/06，清华大学，材料学院，硕士，导师：赵凌云 （生物材料）
2011/09-2015/06，清华大学，材料学院，学士 （材料科学与工程）
工作经历：
2023/07-至今，北京化工大学，生命科学与技术学院，副教授
2018/07-2020/08，广东博智林机器人有限公司，高级经理
主要研究领域：
已期刊发表SCI论文40余篇，H-index为20，授权发明专利4项。
（1）可降解/全降解功能型纳米材料在肿瘤热疗和动力学治疗中的应用；
Chem. Eng. J. 2022, 446, 137310； Adv. Sci. 2022, 9 (4), 2104101； Chem. Eng. J. 2022, 438, 135372； Chem. Eng. J. 2023, 451, 138617； ACS Appl. Bio Mater. 2020, 3 (9), 5845–5855.
（2）可降解/全降解新型纳米药物递送系统用于肿瘤免疫抑制微环境调控研究；
Adv. Healthcare Mater. 2019, 8 (14), 1900203； ACS Appl. Mater. Interfaces 2022, 14 (4), 4995–5008； Nanoscale 2021, 13 (34), 14525–14537； J. Biomedical Nanotech. 2018, 14, 362–370.
（3）基于生物催化的新型纳米酶用于瘤内菌清除协同肿瘤综合治疗应用研究；
Adv Funct Mater 2022, 32 (12), 2107518； Prog. in Mater. Sci.2023, 138, 101145; Nano Res. 2022, 15 (3), 2244–2253; Materials Today Bio 2022, 100411; Bioactive Materials 2021, 6 (3), 602–612.
（4）生命物质的手性界面与肿瘤细胞识别行为研究。
获奖及荣誉：
2023北京市优秀博士毕业生
2023北京化工大学青年后备人才
科研项目：
2023年 教育部重点实验室开放课题，主持
2021年 企事业横向课题，参与
2020年 国家自然科学基金面上项目，参与
2017年 国家自然科学基金面上项目，参与
代表性著作：
[1]W. Xie#, Z. Guo, L. Zhao, Y. Wei, The copper age in cancer treatment: From copper metabolism to cuproptosis, Progress in Materials Science. 138 (2023) 101145. https://doi.org/10.1016/j.pmatsci.2023.101145.
[2]H. Huang, W. Xie#, D. Hu, X. He, R. Li, X. Zhang, Y. Wei, Type I photodynamic therapy with a self-degradable conjugated polyelectrolyte in combination with CpG adjuvant for cancer immunotherapy, Chem Eng J. 451 (2023) 138617. https://doi.org/10.1016/j.cej.2022.138617.
[3]Z. Guo, W. Xie#, X. Gao, J. Lu, J. Ye, Y. Li, A. Fahad, G. Zhang, L. Zhao, Nanoheterostructure by liquid metal sandwich-based interfacial galvanic replacement for cancer targeted theranostics, Small. 19 (2023) 2300751. https://doi.org/10.1002/smll.202300751.
[4]W. Xie#, G. Zhang, Z. Guo, J. Lu, J. Ye, W. Xu, X. Gao, K. Yue, Y. Wei, L. Zhao, Ultra-sensitive iron-doped palladium nanocrystals with enhanced hydroxyl radical generation for chemo-/chemodynamic nanotherapy, Adv Funct Mater. 32 (2022) 2107518. https://doi.org/10.1002/adfm.202107518.
[5]W. Xie#, J. Ye, Z. Guo, J. Lu, W. Xu, X. Gao, H. Huang, R. Hu, L. Mao, Y. Wei, L. Zhao, TME-responded full-biodegradable nanocatalyst for mitochondrial calcium overload-induced hydroxyl radical bursting cancer treatment, Chem Eng J. 438 (2022) 135372. https://doi.org/10.1016/j.cej.2022.135372.
[6]W. Xie#, G. Zhang, Z. Guo, H. Huang, J. Ye, X. Gao, K. Yue, Y. Wei, L. Zhao, Shape-controllable and kinetically miscible copper–palladium bimetallic nanozymes with enhanced fenton-like performance for biocatalysis, Materials Today Bio. 16 (2022) 100411. https://doi.org/10.1016/j.mtbio.2022.100411.
[7]W. Xie#, J. Ye, Z. Guo, J. Lu, X. Gao, Y. Wei, L. Zhao, Ultrafast fabrication of iron/manganese co-doped bismuth trimetallic nanoparticles: a thermally aided chemodynamic/radio-nanoplatform for low-dose radioresistance, ACS Appl Mater Interfaces. 14 (2022) 21931–21944. https://doi.org/10.1021/acsami.2c02484.
[8]H. Huang, W. Xie#, Q. Wan, L. Mao, D. Hu, H. Sun, X. Zhang, Y. Wei, A self‐degradable conjugated polymer for photodynamic therapy with reliable postoperative safety, Adv Sci. 9 (2022) 2104101. https://doi.org/10.1002/advs.202104101.
[9]Z. Guo, X. Gao, J. Lu, W. Xu, J. Ye, Y. Li, W. Xie#, L. Zhao, Recent advances for liquid metals: synthesis, modification and bio-applications, J Mater Sci Technol. 143 (2022) 153–168. https://doi.org/10.1016/j.jmst.2022.08.053.
[10]Z. Guo, W. Xie#, Q. Zhang, J. Lu, J. Ye, X. Gao, W. Xu, A. Fahad, Y. Xie, Y. Wei, H. Wu, C. Boyer, L. Zhao, Z. Gu, Photoactivation-triggered in situ self-supplied H2O2 for boosting chemodynamic therapy via layered double hydroxide-mediated catalytic cascade reaction, Chem Eng J. 446 (2022) 137310. https://doi.org/10.1016/j.cej.2022.137310.
[11]W. Xie#, L. Zhao, Y. Wei, J. Yuan, Advances in enzyme-catalysis-mediated RAFT polymerization, Cell Rep Physical Sci. 2 (2021) 100487. https://doi.org/10.1016/j.xcrp.2021.100487.
[12]Z. Guo, J. Lu, D. Wang, W. Xie#, Y. Chi, J. Xu, N. Takuya, J. Zhang, W. Xu, F. Gao, H. Wu, L. Zhao, Galvanic replacement reaction for in situ fabrication of litchi-shaped heterogeneous liquid metal-au nano-composite for radio-photothermal cancer therapy, Bioact Mater. 6 (2021) 602–612. https://doi.org/10.1016/j.bioactmat.2020.08.033.
[13]D. Wang, W. Xie#, Q. Gao, H. Yan, J. Zhang, J. Lu, B. Liaw, Z. Guo, F. Gao, L. Yin, G. Zhang, L. Zhao, Non‐magnetic injectable implant for magnetic field‐driven thermochemotherapy and dual stimuli‐responsive drug delivery: transformable liquid metal hybrid platform for cancer theranostics, Small. 15 (2019) 1900511. https://doi.org/10.1002/smll.201900511.
[14]F. Gao, T. Zhang, X. Liu, A. Ghosal, D. Wang, W. Xie#, Y. Li, X. Wang, L. Tao, J. Yu, Y. Wei, H.M. Fan, L. Zhao, Nonmagnetic hypertonic saline-based implant for breast cancer postsurgical recurrence prevention by magnetic field/pH-driven thermochemotherapy, ACS Appl. Mater. Interfaces. 11 (2019) 10597–10607. https://doi.org/10.1021/acsami.9b02013.
教师寄语:
天行健·君子以自强不息，不要忘记当初带着梦想出发时的自己！
招生要求：
对科研：岁月漫长心怀热爱；对未来：星辰大海携手共赴