姓名：陈光
职称：副教授
办公地址：科技大厦西106 |  |
教育背景：
1998,9-2003,7: 沈阳药科大学中药学院，硕博连读
1993,9-1998,7: 沈阳药科大学，日语药学专业（5年制）
工作经历：
2001,3月-2002年5月：日本高知大学医学部（外国人研究者）
2003年10月-2005年10月：清华大学生物系（博士后）
主要研究领域：
1. 天然药物生物活性、毒性物质基础
2. 天然产物活性机制及体内代谢
3. 植物源农药的发现及作用机制
4. 中药透皮制剂
代表性著作：
1. Shu-Xian Zhang, Si-Tong Lv, Shi-An Meng, Wen-Xian Du, Yi Li, Guang Chen*. Crop protection potential of the leaves of Juglans mandshurica Maxim.: The phenoloxidase promoting related insecticidal effect of its ethanolic extract. Industrial Crops and Products, 2023, 204 (PartB): 117331.
2. Qiao Gao, Wen-Xian Du, Si-Tong Lv, Shi-An Meng, Guang Chen*. Insecticidal effect of green walnut husks and its active basis digesting targeting to insect phenoloxidase using UPLC-Q-TOF-MS coupled with PLS analysis. Phytoparasitica, 2023, https://doi.org/10.1007/s12600-023-01103-9
3. Qiao Gao, Li-Xiang Zhou, Rong Huang, Shu-Xian Zhang, Guang Chen*. Five New Glycoside Constituents from the Roots of Gentiana crassicaulis Duthie ex Burk. Chemistry & Biodiversity, 2023, 20 (8): e202300841.
4. Huan Liu, Huan Zhao, Wen-Yi Hu, Hai-Min Hu, Shu-Bing Hou, Guang Chen*. A new strategy for the preparation of total iridoids from Radix Gentianae Macrophyllae and anti-inflammatory profile digesting by UPLC-Q-TOF-MS characterization coupled with PLS analysis. Industrial Crops and Products, 2021, 168: 113586.
5. Huan Liu, Huan Zhao, Rong Huang, Amur Safdar Ali, Xin Wang, Shi-An Meng, Guang Chen*. A new and effective evaluation method for Radix Gentianae Macrophyllae herbs based on 2-phenylethyl β-D-glucopyranoside, 2-methoxyanofinic acid and gentioxepine by UPLC-QTOF-MS exploring and HPLC-DAD quantification. Biomedical Chromatography, 2021, 35: e5046.
6. Shu-Bing Hou, Xin Wang, Rong Huang, Huan Liu, Hai-Min Hu, Wen-Yi Hu, Si-Tong Lv, Huan Zhao, Guang Chen*. Seven new chemical constituents from the roots of Gentiana macrophylla pall. Fitoterapia, 2020, 141: 104476.
7. Rong Huang, Wen-Yi Hu, Shu-Bing Hou, Huan Zhao, Xin Wang, Guang Chen*. The chemical constituents of Gentiana macrophylla pall. under acidic condition using gentiopicroside-rich secoiridoids extract. Phytochemistry Letters, 2020, 39: 30-34.
8. Rong Huang, Xin Wang, Huan Liu, Hai-Min Hu, Wen-Yi Hu, Guang Chen*. Chemical constituents from Gentiana crassicaulis Duthie ex Burk. Biochemical Systematics and Ecology, 2020, 92: 104115.
9. Huan Zhao, Qiao-Lian Wang, Shu-Bing Hou, Guang Chen*. Chemical constituents from the rhizomes of Polygonatum sibiricum Red. and anti-inflammatory activity in RAW264.7 macrophage cells. Natural Product Research, 2019, 33 (16): 2359-2362.
10. Si-Tong Lv, Wen-Xian Du, Shu-Min Bai, Guang Chen*. Insecticidal effect of juglone and its disturbance analysis in metabolic profiles of Aphis gossypii glover using 1H NMR-based metabonomics approach. Phytoparasitica, 2018, 46: 521-531.
11. Wen-Yi Hu, Wen-Xian Du, Shu-Min Bai, Si-Tong Lv, Guang Chen*. Phenoloxidase, an effective bioactivity target for botanical insecticide screening from green walnut husks. Natural Product Research, 2018, 32 (23): 2848-2851.
12. Shu-Min Bai, Hong-Mei Ren, Guo-Jun Zheng, Guang Chen*. Senobtusin, a novel alkaloid with amidine moiety from Senecio obtusatus Wall. ex DC. Natural Product Research, 2017, 31 (20): 2450-2453.
13. Min Cui, Qiao-Lian Wang, Guang Chen*. Serum metabolomics analysis reveals changes in signaling lipids in breast cancer patients. Biomedical Chromatography, 2016, 30 (1): 42-47.
14. Guang Chen, Xin-Mei, Chang-Yuan Yu. A new naphthalenone isolated from the green walnut husks of Juglans mandshurica Maxim. Natural Product Research, 2015, 29 (2): 174-179.
15. Li-Ming Li, Qi-Peng Yuan, Guang Chen*. Four homoisoflavonoids isolated from traditional Chinese medicine: “Gan Luo Xin”. Journal of Asian Natural Products Research, 2014, 16 (8): 813-818.教师寄语：
天道酬勤，只要努力付出，好运总会眷顾你。
招生要求：
动手能力强，踏实、勤奋，善于发现和解决问题。