陈必强

发布时间:2019-10-31

姓名:陈必强 

 

职称:教授

 

邮箱:chenbq@mail.buct.edu.cn   

 

工作地点:科技大厦西配楼503


教育背景:

2001 学士,生物化工(北京化工大学)

2003 硕士,生物化工(北京化工大学)

2008 博士,生物化工(北京化工大学)

2006/01-2006/07 赴丹麦技术大学进行博士联合培养

2008.8-2010.6 博士后(清华大学化工系)


工作经历:

2010.8-2014.12,北京化工大学生命学院,副教授,硕士生导师

2015.1-2018.1,北京化工大学生命学院,见习教授,硕士生导师

2018.1-至今,北京化工大学生命学院,教授,博士生导师


学术兼职:

lJournal of Molecular Catalysis B: Enzymatic,RSC Advance, Applied Microbiology and Biotechnology等国际期刊审稿人


主要研究领域:

长期从事生物催化剂工程的研究。作为项目负责人主持国家自然科学基金2项、国家973计划子课题2项、863计划子课题1项,企业横向课题2项。近年发表SCI论文30多篇,申请专利11项(已授权6项,包括国际专利1项)。具体研究方向:

l新酶的筛选与酶的蛋白质工程改造

l酶的固定化微环境调控

l多酶催化体系构建

l新型酶反应器设计与酶反应过程在线监测、控制与系统集成

l生物催化新产品、新工艺开发


获奖及荣誉:

2008年“以脂肪酶为催化剂的化学品绿色合成工艺”获国家技术发明奖二等奖(第二完成人)

2005年“以脂肪酶为催化剂的绿色化学合成工艺”中国石化技术发明一等奖(第三完成人)

2010年获教育部“10000个科学难题”突出贡献奖

2011获年中国微生物学会酶工程专业委员会“青年优秀论文奖”

2013年入选北京市青年英才计划

2016年入选北京市科技新星计划


代表性著作:

Selected Publications:

1)Cui C, Chen H, Chen B*, et al. Genipin Cross-Linked Glucose Oxidase and Catalase Multi-enzyme for Gluconic Acid Synthesis (2016). Applied Biochemistry and Biotechnology, 1-10.

2)Cui, C., Nan, G., Chen, X., Chen, B*., & Tan, T*. (2016). Immobilization of yarrowia lipolytica, lipase ylip 2 for the bioicatalytic synthesis of phytosterol ester in a water activity controlled reactor. Colloids & Surfaces B Biointerfaces, 146, 490-497.

3)Cui, C., Zhen, Y., Qu, J., Chen, B*., & Tan, T*. (2016). Synthesis of biosafe isosorbide dicaprylate ester plasticizer by lipase in a solvent-free system and its sub-chronic toxicity in mice. Rsc Advances, 6(15), 11959-11966.

4)Tao, Y., Dong, R., Pavlidis, I. V., Chen, B*., & Tan, T. (2015). Using imidazolium-based ionic liquids as dual solvent-catalysts for sustainable synthesis of vitamin esters: inspiration from bio- and organo-catalysis. Green Chemistry, 18(5), 1240-1248.

5)Tao, Y., Chen, G., Pavlidis, I. V., Jiang, Y., Qie, L., & Cui, C., Liu L., Chen, B*, & Tan, T.* (2015). Water-dependent kinetics guide complex lipase-mediated synthesis of biolubricants in a water activity control reactor. Catalysis Science & Technology, 5(12), 5120-5128.

6)Cui, C., Tao, Y., Ge, C., Zhen, Y., Chen, B*., & Tan, T*. (2015). Synergistic effects of amine and protein modified epoxy-support on immobilized lipase activity. Colloids & Surfaces B Biointerfaces, 133(1), 51-57.

7)Rong, X., Cui, C., Chen, B*., & Tan, T. (2015). Immobilizing yarrowia lipolytica, lipase lip2 via improvement of microspheres by gelatin modification. Applied Biochemistry & Biotechnology, 177(3), 1-9.

8)Cui, C., Xie, R., Tao, Y., Zeng, Q., Chen, B*, & Tan T*. (2015). Improving performance of yarrowia lipolytica, lipase lip2-catalyzed kinetic resolution of (R,S)-1-phenylethanol by solvent engineering. Biocatalysis & Biotransformation, 33(1), 38-43.

9)Tao, Y., Cui, C., Shen, H., Luo, L., Chen, B*., & Tan, T*. (2014). Enhancing trimethylolpropane esters synthesis through lipase immobilized on surface hydrophobic modified support and appropriate substrate feeding methods. Enzyme & Microbial Technology, 58-59(9), 60-67.

10)Chen, Biqiang,Zhang, Hong,Cheong, Ling-Zhi,Tan, Tianwei,Xu, Xuebing ,Enzymatic Production of ABA-Type Structured Lipids Containing Omega-3 and Medium-Chain Fatty Acids: Effects of Different Acyl Donors on the Acyl Migration Rate,Food and Bioprocess Technology,2012,5(2):541-547

Book Chapters:

1)Biqiang Chen, Yifeng Tao, Meng Wang, Di Cai, Tianwei Tan: Bioconversion of Biomass to Bulk Chemicals. Sustainable Production of Bulk Chemicals, 01/2016; , ISBN: 978-94-017-7473-4

2)陈必强,雷二庆、邢婉丽、刘冉、刘录祥、李奎、邱文德、李俊、刘洁,生物产业,《2017中国战略新兴产业发展报告》,中国工程科技发展战略研究院, 科学出版社, pp 124-146, 中国, 2016/11/10   


教师寄语:

说真话


招生要求:

勤奋、开朗