王少杰

发布时间:2022-03-18

 

  

姓名:王少杰

 

职称:副教授

 

邮箱:wangshaojie@mail.buct.edu.cn

 

办公地址:东校区科技大厦西配楼113



教育背景:

2009.09-2013.07,北京化工大学,生物工程,学士

2013.09-2019.07,北京化工大学,化学工程与技术,博士

2015.09-2016.10,上海交通大学,联合培养博士

2017.11-2018.11,Washington University in St. Louis,访问学者


工作经历:

2019.07-2021.08,上海交通大学,纳米生物医学工程研究所,博士后

2021.09-至今,北京化工大学,生命科学与技术学院,副教授


学术兼职:

Synthetic and Systems BiotechnologyFermentation等期刊客座编辑,Water ResearchChemical Engineering JournalBioresource TechnologyBiotechnology Advances等期刊审稿人,中国化工学会会员


主要研究领域:

1)全基因组尺度代谢网络模型理性设计

构建并优化全基因组尺度代谢网络模型,整合复合约束提升模型模拟精度,分析代谢调控靶点和途径改造策略,理性指导细胞工厂的设计与构建。

2)高性能微生物单/多菌细胞工厂构建

基于代谢网络模型构建与模拟设计,结合代谢工程与合成生物技术,开发高性能微生物单/多菌细胞工厂,实现功能氨基酸、生物能源、生物基材料单体等产品的高效合成。


学术成绩:

入选北京市科协青年人才托举工程,主持国家自然基金面上项目、青年项目、北京市自然基金面上项目、国家重点研发子课题、中国博士后基金项目、企业合作项目等10余项。以第一或通讯作者在Adv. Sci.Biotechnol. Adv.Water Res.等知名国际期刊上发表论文30余篇,申请专利5项,获批软件著作权3项。指导学生获得北京市优秀本科生毕业论文、全国大学生可再生能源优秀科技作品竞赛全国一等奖等多项奖励。


代表性著作:

1.         Liu, Y., Xue, B., Wang, S*. & Su, H*. Model-Guided Rational Construction of Escherichia coli Synthetic Consortia for Enhanced 2-Methylbutyric Acid Production. 2025, Adv. Sci.2416272, 1–13.

2.         Yang, C., Zhao, Y., Xue, B., Wang, S*. & Su, H*. PYF: A multi-functional algorithm for predicting production and optimizing metabolic engineering strategy in Escherichia coli microbial consortia. Brief. Bioinform.2025, 26, bbaf295.

3.         Xue, B., Liu, Y., Yang, C., Liu, H., Yuan, Q., Wang, S.*, & Su, H*. Cultivated enzyme constraint metabolic network model for rational guidance in constructing synthetic consortia to achieve optimal pathway allocation prediction. Adv. Sci., 2024, 11(9): 2306662.

4.         Xiong, W., Jin, Y., Wang, Y., Wang, S.*, Chen, B., & Su, H*. Novel insights into the biological state in algal-bacterial granular sludge granulation: Armor-like protection provided by the algal barrier. Water Res., 2024, 262: 122087.

5.        Liu, Y., Xue, B., Liu, H., Wang, S.*, & Su, H*. Rational construction of synthetic consortia: Key considerations and model-based methods for guiding the development of a novel biosynthesis platform. Biotechnol. Adv., 2024, 72: 108348.

6.         Xiong, W. #, Wang, S. #, Zhang, Q., Hou, Y., Jin, Y., Chen, B., & Su, H*. Synergistic analysis of erformance, microbial community, and metabolism in aerobic granular sludge under polyacrylonitrile microplastics stress. Bioresour. Technol., 2023, 385: 129394.

7.         Li, J., Wang, K., Wang, S*. & Su, H*. Spatially-ordered layer-by-layer biofilms of a two-species microbial consortium promote hydrogen production.Renew. Energy 2023, 215, 118905.

8.         Wang, Y., Zhao, Y., Wang, S*., Xiao, G.*, Jin, Y., Wang, Z., & Su, H*. Visible-Light-Driven Enhanced Biohydrogen Production by Photo-Biohybrid System Based on Photoelectron Transfer between Intracellular Photosensitizer Gold Nanoparticles and Clostridium butyricum.ACS Sustain. Chem. Eng. 2023, 11, 300–311.

9.         Cui, P. #, Wang, S#. & Su, H*. Enhanced biohydrogen production of anaerobic fermentation by the Fe3O4 modified mycelial pellets-based anaerobic granular sludge. Bioresour. Technol. 2022, 366, 128144.

10.     Cui, P., Ge, J., Chen, Y., Zhao, Y., Wang, S*., & Su, H*. The Fe3O4 nanoparticles-modified mycelium pellet-based anaerobic granular sludge enhanced anaerobic digestion of food waste with high salinity and organic load. Renew. Energy 2022,185, 376–385.


教师寄语:

业精于勤,荒于嬉;行成于思,毁于随。


招生要求:

勤奋、思辨、善于交流