您目前的位置: 首页» 学生动态

百济神州(北京)生物科技有限公司招聘

资深科研员(生物药部)—免疫生物学、肿瘤免疫学、抗体与靶点蛋白相互作用的功能分析

 

工作职责:

主要职责是利用免疫生物学、分子免疫学的实验手段对药物靶点蛋白进行功能分析,确定靶点蛋白在动员免疫系统, 活化特定的抗肿瘤免疫细胞(如CD8+cytotoxic T-lymphocyte, NK cell)中的作用; 研究抗体与靶点的作用机理。具硕士学历并具有较丰富的免疫学实验经验者可考虑较高职称。

 

任职要求:

生物学本科/免疫学硕士学历 能熟练地从人和动物的血液样品中分离PBMC 细胞,利用抗体交联的磁性珠吸附技术分离各种免疫细胞,如B-淋巴细胞,CD4+T-淋巴细胞, CD8+cytotoxic T-淋巴细胞, NK 细胞; 并用分离免疫细胞对靶点蛋白和抗体进行功能分析、测定 能熟练利用ELISA技术对培养液和血清中的各种生长因子进行定量分析 如能操作FACS仪器,对细胞表面的受体蛋白进行定性、定量分析,将获优先考虑 能用Excel或其他分析软件独立分析实验结果、制作图表,记录实验结果并用PowerPoint写出实验报告 具有一定英语阅读和写作能力者

Senior Scientist in Biologics Department – Immunology, Cancer Immunology, Antibody and Target interaction and functional analysis

 

Responsibilities:

The applicant will utilize immunological, cancer biology method to analyze antibody function, to understand the mechanisms by which antibody acts on the immune target protein and mobilize immune cells such as CD8+cytotoxic T-lymphocytes, NK cells and dendritic cells. Applicant with research experience in cancer immunology and antibody technology work may be considered for higher position.

 

Requirement:   

Master degree in immunology, cell biology and molecular biology Experienced in handling human and animal blood samples, and capable of isolating PBMCs from the blood samples as well as other immune cells e.g. CD8+ and CD8+ T-lymphocytes, B-cell, etc. Good at using ELISA method to analyze cytokines and growth factors secreted from immune cells Good at performing FACS to analyze antibody binding activity to cell surface target Familiar with using Microsoft Excel, Prism to analyze data Certain English reading and writing ability

 

 

 

 

资深科研员(药研生物部)

 

主要职责:

支持小分子药物开发的作用机制研究,细胞检测方法的开发,优化,验证和操作。

 

任职要求:

需要具备医学/免疫学/分子生物学/细胞生物学/药理学等专业的硕士学位 掌握常用技术:细胞培养及转染,免疫检验技术/西方印记/ELISA/IP, DNA,RNA和蛋白质技术,PCR技术 能承担多任务,良好的沟通能力,团队合作精神 有制药领域检测技术经验者优先 有肿瘤或免疫学细胞信号通路研究经历 有工作热情,有创造力,有解决问题能力,逻辑思考能力强者最佳

 

Senior Scientist in Discovery Biology Department

 

Responsibilities:

The primary responsibilities are to study the mechanism of action, to develop, optimize, validate and execute cellular assays to support small molecule drug discovery projects.

 

Requirements:

Candidates are expected to have a master degree or equivalent certificate in Medicine/Immunology/ Molecular Biology/Cell Biology/Pharmacology areas Candidates should have proven competences in standard techniques, including cell culture and transfection; immunoassays/Western blot/ELISA/IP; DNA/RNA/Protein manipulations; PCR analysis Multi-tasking, good communication skills and team work spirit are required A pharmacologist with drug discovery experience is preferred. Expertise in various assay technologies (ELISA, TR-FRET, HTRF, GRA) a plus Experience in cell signaling transduction in oncology and immunology is desired Competency of self-motivation, creativity, problem-solving, logic thinking is preferred

 

 

 

 

 

 

 

 

 

 

 

 

资深科研员(化学部)

 

工作职责:

独立完成文献的查阅,依据文献完成化合物合成路线的初步设计 熟练地完成化学反应,细心观察实验,规范操作,并对结果做出较全面的分析 具有较强的实验动手能力和解决问题能力,能独立进行多步有机合成的实验工作 清晰完整地完成实验记录,包括结论,下一步计划及产品的结构鉴定 科学分析实验中出现的问题,提出合理的改进建议,或得出合理的结论

 

任职要求:

熟悉有机合成、药物研发,欢迎硕士应届毕业生加盟 具有丰富的有机合成知识和经验,能够独立地设计和进行多步有机合成反应 熟练使用和操作有机合成实验室的各种仪器 熟练掌握常用的有机化合物分离提纯技术及化合物结构解析能力 能够熟练地检索和运用各种化学文献及专利 有责任心、敬业、创新,有较强的团队协作能力

 

Senior Scientist in Chemistry Department

 

Responsibilities:

Search literature, and design synthetic route independently Conduct experiments to explore the scope and limitations of the synthetic methodology, to support conclusions regarding reaction mechanisms Synthesize organic compounds with multi steps independently, efficiently, safely, and reproducibly Carefully observe the experience, accurately operate, get rational outcome Maintain an accurate and complete experimental record, including conclusions, hypotheses for next steps to be taken, and thorough characterization of products Develop sound mechanistic understanding of observed experimental results

 

Requirements:

Master degree in Organic Chemistry or Medicinal Chemistry Skilled synthetic chemist with the ability of design and conduction of organic experiment Skilled in operation of all kinds of instruments and apparatus in organic chemistry lab Strong knowledge of techniques related to purification and characterization of organic compounds Skilled in literature searching about organic and medicinal chemistry Strong sense of responsibility, devotion, innovation and team work

 

 

 

 

研究员(化学部)

 

工作职责:

独立完成文献的查阅和图谱解析,依据文献完成化合物合成路线的初步设计 能够发现并有效的解决问题 作为管理人员,负责实验室人员管理、指导实验,培训科研人员 与公司内部人员和外部人员能够进行相关数据上的沟通与交流

 

任职要求:

熟悉有机合成、药物研发,欢迎博士应届毕业生加盟 较强的有机化学背景为佳 具有丰富的有机合成知识和经验,能够独立地设计和进行多步有机合成反应 具有丰富的有机化学和药物化学文献查阅的能力 有责任心、敬业、创新,有较强的团队协作能力

 

Research Investigator in Chemistry Department

 

Responsibilities:

Search literature and design molecular and synthetic route independently Identify chemistry issues and solve problem efficiently Lead in the lab as a manager who takes responsibility for people, scientific direction and for training chemists Communicate data inside and outside the company

 

Requirements:

Doctor degree in Organic Chemistry or Medicinal Chemistry Strong knowledge of organic chemistry Highly skilled synthetic chemist with the ability of design and conduction of organic experiment Highly skilled in literature searching about organic and medicinal chemistry Strong sense of responsibility, devotion, innovation and team work

 

 

 

请有意向的同学将简历投至  hr@beigene.com   并注明自己姓名+学历+专业名称